Author: Revc, Golden Finance
After the great abundance of materials, crypto whales, like technology giants, began to pay attention to the "immortality" biotechnology track.
On November 13, Binance founder CZ posted a dynamic on the social platform X, sharing his feelings about participating in a small decentralized science (DeSci) entrepreneur gathering organized by Binance Labs, and attached a photo with Ethereum founder Vitalik. At the event, Vitalik introduced CZ to VitaDAO's first longevity product, VD001, a natural high-dose spermidine supplement approved by the Thai Food and Drug Administration. CZ said in the interaction that he hopes to see the emergence of 1,000 DeSci-related projects next year.
And on November 8, Binance Labs announced that it had invested in BIO Protocol. The BIO platform enables scientists, patients, and investors around the world to co-fund, develop, and co-own new drugs and therapies. Currently, BIO's network consists of seven BioDAOs, focusing on diverse areas such as cryopreservation, women's health, and psychedelics for mental health.
And crypto users with a keen sense of smell seized the Desci hotspot over the weekend and participated in the carnival of MEME tokens with a market value of tens of millions of dollars.
DeSciRelated Project Introduction
Bio Protocol
Bio Protocol is a new financial protocol designed for decentralized science (DeSci) that aims to accelerate the flow of capital and talent into scientific research through on-chain mechanisms. Its core goals include:
1. Create and support the BioDAO network to provide on-chain funding and liquidity for scientific research.
2. Standardize the BioDAO framework, economic model and data products to improve the efficiency of the generation and commercialization of scientific intellectual property (IP) and data.
3. Provide continuous funding and liquidity to meet the long-term development needs of scientific research.

Core Operation Module
BIO Protocol achieves its goals through the following five core functions:
1. Curation:
- Use $BIO tokens to screen new BioDAO projects and select high-quality projects through community voting.
- Holders use locked vBIO tokens to show support, and successful projects will receive funding, support and market priority.
2. Funding:
- Provide initial seed round financing opportunities for selected BioDAOs, and participants can obtain the same or even better conditions as institutional investors.
- Ensure a high degree of consistency between research and community participation.
3. Liquidity:
- Provide market liquidity for BioDAO through BIO tokens and other assets held by the BIO Treasury (such as ETH).
- Reduce exchange costs and accumulate protocol liquidity (POL) through liquidity pools (e.g., VITA/BIO, BIO/ETH).
4. Rewards (Bio/acc Rewards):
- Issue BIO tokens as rewards to incentivize BioDAO to achieve milestones (such as advancing IP to the clinical stage or achieving sales revenue).
5. Meta-Governance:
- BIO holds tokens of multiple BioDAOs, giving the community governance rights over the entire ecosystem (BioDAO and IP assets).
BIO Protocol's value sources include:
1. Token allocation:
- Provide $100,000 in funding to the new BioDAO in exchange for its 6.9% token allocation; at the same time, the BIO Treasury can hold interests in its scientific IP.
2. Protocol Own Liquidity (POL):
- Continue to add value to the BIO Treasury through liquidity pool income (BIO, BioDAO tokens, IP tokens, ETH, etc.).
3. BIO Token Usage:
- Plan BioDAO's selection and funding plans.
- Priority participation in BioDAO's token and IP sales.
- Enjoy discounts on BioDAO products/services.
- Vote on fund allocation and protocol updates in governance.
Currently, the 2.5th round of BIO token auction has been completed, raising approximately $58 million, but the tokens are not yet in circulation, and there are only about 3,200 holders, who are mainly institutions and large investors. In addition, the token has an inflation mechanism, and the details are to be determined.

pump.science
Currently, there are three MEME tokens under the Desci concept that have been chased by major funds, and the market value of RIF has reached 180 million US dollars.

Rifis deployed bypump.science. The project has been strictly screened and examined.Desciis different fromtraditionalMEME.It has a higher threshold for asset issuance.Pump.Scienceis adecentralizedscience(DeSci)basedontheSolanablockchain. Platform, aims to promote longevity research. The project is funded by the Solana Foundation, combining IP-tokenization and real-time experimental transparency to encourage community participation in scientific research. Its core experiments are mainly compound testing, including Urolithin A ($URO) and Rifampicin ($RIF), with test subjects ranging from worms to humans, and gradually unlocking experiments through market valuations (such as $69k for worms and $10m for humans). Experimental data is live-streamed in real time, similar to Twitch's scientific transparency model, and anyone can submit compound suggestions to participate in testing.

Rif
RIF is an experimental research token for the antibiotic rifampicin, which has attracted medical attention for its potential anti-aging effects. Studies on model organisms such as C. elegans have shown that rifampicin activates cellular defense mechanisms and enhances resistance to stress and damage. It helps reduce oxidative stress and maintain protein quality within cells, promoting healthier and longer life in these organisms. Although the research is still in the early stages and its use in humans has not yet been confirmed, rifampicin's ability to enhance cell health makes it a promising candidate for the development of anti-aging therapies.

As of 6:00 p.m. Beijing time on the 18th, RIF's 24-hour increase exceeded 129%, with a market value of nearly US$200 million. As the leader of the track, it continues to trigger market Fomo sentiment. A smart money opened a position in RIF at a low point and made a profit of 74 times.

Uro
Uro is an experimental research token for Urolithin, a natural compound produced by human intestinal microorganisms through the metabolism of ellagitannins (active ingredients such as those found in pomegranates), which has unique biological functions in cell health. It clears out old or dysfunctional mitochondria by activating "mitophagy" to support the generation of new mitochondria. This process helps cells optimize energy metabolism and improve overall efficiency and vitality. In animal studies, urolithin A has been shown to extend the lifespan of Caenorhabditis elegans, demonstrating its anti-aging potential.
It also rose 113% in the past 24 hours, with a market value of nearly US$70 million.

SCIHUB
SCIHUBFocusing on academic freedom and a backlash against the long-standing monopoly of the academic publishing industry, Sci-Hub was founded by Russian Alexandra Elbakyan to provide free access to academic papers and help users overcome the high cost of downloading research articles. Elbakyan faced financial barriers as a student and founded Sci-Hub after teaching herself programming. Sci-Hub is particularly popular in China, where Chinese users account for a large portion of its traffic and donations. The platform has faced multiple lawsuits, mostly from publishers such as Elsevier, and its domains and social media accounts have been blocked. Despite the legal challenges, Elbakyan has relied on crowdfunding to keep the service running. The platform's existence highlights ongoing problems in the academic publishing industry, where high subscription fees limit access to scholarly research. Many researchers support Sci-Hub because it is convenient and easy to use. Elbakyan hopes to restore Sci-Hub's paper upload function and introduce AI features to enhance its service. In China, Sci-Hub is affectionately called "Little Bird" and Elbakyan is hailed as the "Academic Goddess." Sci-Hub's logo consists of a hammer and sickle and a key, symbolizing its stance in the copyright fight. The following is the main process of the struggle:
In May 2017, Elsevier submitted to the court a list of 100 articles illegally provided by Sci-Hub and LibGen, requesting the court to issue a permanent injunction and claiming $15 million. On June 21 of the same year, the U.S. District Court in New York ruled in favor of Elsevier after a trial in absentia. Subsequently, on November 6, 2017, the court ordered Sci-Hub to pay $4.8 million to the American Chemical Society (ACS) and blocked its servers and domains. Despite this, Elbakyan told The Scientist that she would not pay the damages. In December 2018, a Russian court blocked several domains associated with Sci-Hub at the request of a lawsuit by British publisher Springer Nature. In January 2021, Twitter banned Sci-Hub for publishing pirated papers. From a narrative perspective, SCIHUB is more likely to arouse widespread sympathy and resonance with the long-term oppression of industry scholars. From this point of view, MEME has evolved into a community emotional expression of social inequality. In the past 24 hours, SCIHUB has also recorded a 158% increase, with a market value of 50 million US dollars.

Conclusion
The Desci track has demonstrated its independence in project review and application. Combined with the launch method of MEME assets, cutting-edge scientific exploration has been supported by "community finance", but the implementation of related concepts is uncertain. Investors need to pay attention to related risks. From the financing operation of BioProtocol to the issuance of assets to the PumpFun market, the team has a high degree of professionalism, but it should also consider whether excessive financial speculation has deviated from the original intention of the experiment. Whether Desci is close to us or just a "vision" of the super-rich is no longer important in the eyes of investors in the short term.
If we use a sentence to simply summarize the current hot MEME market, Initial Emotion Offering may be a relatively appropriate understanding. The more likely it is to trigger people's emotional resonance, such as Pnut hamsters and SciHub, the more likely it is to bring excess returns in the context of a bull market.